Lilian Spencer, Ph.D.

Biologist in the area of cellular biology and parasitology at the Central University of Venezuela (UCV).
PhD in Medical Research at the National Institute for Medical Research (now called Francis Crick Institute); London, England. PhD Supervisor Professor Anthony Holder. Title of PhD project: Monoclonal antibodies binding to malaria merozoite surface proten-1 protect in vivo against Plasmodium yoelii infection.
Worked in research in the development of immunological tests for Tropical Diseases at the Institute of Tropical Medicine-UCV.
Full Professor at the Simón Bolívar University in the Department of Cellular Biology.
Currently, Professor at the School of Biological Sciences and Engineering at Yachay Tech University.

Research interests

Designs in immunological diagnostic tests in Diseases. Production of monoclonal antibodies and Evaluation of experimental drugs. Biological and immunological evaluation of medicinal plant extracts. Controlled evaluation of drugs in Biomaterials.

Selected Publications

1. Spencer-Valero, L.; Ogun, S. A.; Fleck S.L.; Ling, I.; Scott-Finnigan, T.; Blackman, M. J.; and Holder, A.A. (1998). Passive immunization with antibodies against three distinct epitopes on Plasmodium yoelii merozoite surface protein-1 suppresses parasitemia. Infection and Immunity. Aug; 66(8): 3925-3930.
2. Karen E. Sánchez and Lilian M. Spencer*. Pregnancy-Associated Malaria: Effects of Cytokine and Chemokine Expression. (2022). Travel Medicine and Infectious Disease. 47 (2022) 102282. https://doi.org/10.1016/j.tmaid.2022.102282.
3. Mishell Ortiz, Hortensia Rodríguez, Elisabetta Lucci, Julieta Coro, Beatriz Pernia, Abigail Montero, Francisco Javier Tingo-Jácome, Leslie Espinoza and Lilian M. Spencer*. (2023). Serological cross-reaction between six Thiadiazine by indirect ELISA test and their antimicrobial activity. Methods and Protocols. 2023, 6, 37. https://doi.org/10.3390/mps6020037.
4. Angibelle Rodríguez Gil de Montes and Lilian Maritza Spencer*. (2023). Chimeric antigen receptor T cells: immunotherapy for the treatment of leukemia, lymphoma and myeloma. Mol Cancer Ther. Aug 19;MCT-23-0043; https://doi.org/10.1158/1535-7163.MCT-23-0043.
5. Katherine Stefania Loachamin Gualotuña, Lilian M Spencer*, Hortensia Rodriguez, Abigail Montero-Calderon, Beatriz Pernia, Julieta Coro, Margarita Suarez, Francisco Javier Tingo-Jácome, Zully J. Rodriguez Parra,José Manuel Lozano, Jesús A. Cortés-Vecino. (2023). Antimalarial evaluation of alkyl-linked bis-thiadiazine derivatives in murine model infected with two Plasmodium strains. ADMET and DMPK(2023), Publicado 30 de Noviembre, https://doi.org/10.5599/admet.2105.